Plenary Lecture 2
Oct. 15th (Tue), 15:00-15:40, Conference Hall
Title: New concept pain medicine with regenerative capability, using gene therapy approach:
Scientific basis and results from phase III study for diabetic peripheral neuropathy
Speaker: Sunyoung Kim (Helixmith Co., Ltd., Korea)
1. Understanding of Viral Pathogenesis in Human Cytomegalovirus (HCMV)
• Role of anti-oxidative stress genes in viral infection.
2. Development of New and Innovative Drugs
• Gene-based medicines
3. Development of improved gene delivery vectors and their applications in animal models and human systems.
• Molecular and cell biological understanding of traditional herbal medicines.
1986년 박사: 옥스포드대학교, 분자유전학
1982년 석사: MIT, 생물공학
1978년 학사: 서울대학교 미생물학과
1990년 - 1992년: 미국 하버드대 의과대학 조교수
1992년 - 2018년: 서울대학교 생명과학부 교수
1996년 - 현 재: ㈜헬릭스미스: 설립자, 현 CEO (대표이사)
2006년 - 2008년: 한국유전자세포치료학회 (KSGCT) 초대, 2대 학회장
※ 주요 매체 (조선, 중앙, 한겨례, KBS TV 등)의 칼럼니스트, 객원 논설위원, 기고 활동
1. Jyhyun Ahn, Jiwon Jang, Junsub Lee, Seo-ho Oh, Junghun Lee, Keejung Yoon, and Sunyoung Kim, 2014: GSK3β, but not GSK3α, inhibits the neuronal differentiation of neural progenitor cells as a downstream target of mTORC1. Stem Cells and Development, 23(10), 1121-1133.
2. Doo Suk Lee, Jinyong Choi, Seon-Hee Kim, and Sunyoung Kim, 2014: Ameliorating effects of HX106N, a water-soluble botanical formulation, on Aβ25-35-induced memory impairment and oxidative stress in mice. Biol Pharm Bull., 37(6), 954-960.
3. Jinyong Choi, Junsub Lee, Junghun Lee, Seon-Hee Kim, Jiyoung Kim, and Sunyoung Kim, 2013: PG201 downregulates the production of nitrite by upregulating heme oxygenase-1 expression through the control of phosphatidylinositol 3-kinase and NF-E2-related factor 2. Nitric Oxide, 33, 42-55.
4. Donghyun Kim, Jinyong Choi, Mi-Jeong Kim, Seon Hee Kim, Sang Heon Cho, and Sunyoung Kim, 2013: Reconstitution of anti-allergic activities of PG102 derived from Actinidia arguta by combining synthetic chemical compounds. Experimental Biology and Medicine, 238, 631-640.
5. Jiwon Jang, Jyhyun Ahn, Nayeon Lee, Seong-Tae Kim, Dae-Hyuk Kweon, Jae Youl Cho, Kye Won Park, Sunyoung Kim, and Keejung Yoon, 2013: Ultrasound Backscatter Microscopy Image-Guided Intraventricular Gene Delivery at Murine Embryonic Age 9.5 and 10.5 Produces Distinct Transgene Expression Patterns at the Adult Stage. Molecular Imaging, 1(12(8)), 485-90.